Age-standard functions out-of 86,149 feamales in the brand new NHS We in the 1994 and 94,715 ladies in the fresh new NHS II for the 1995 by quintiles regarding magnesium, potassium, and you may calcium supplements consumption step one
Design 2 was modified in terms of model step 1 as well as for intakes out of potassium and you may calcium supplements (quintiles out-of g/d)
From the multivariate analyses, full and you can fat reduction magnesium intakes was indeed inversely of likelihood of total however, ischemic or hemorrhagic coronary attack ( Desk dos). This new pooled multivariate RR getting overall stroke was 0.87 (95% CI: 0.78, 0.97; P-trend = 0.07) to your research of females from the higher having reduced quintiles of complete magnesium consumption; whereas brand new pooled multivariate RR into the research from highest with low quintiles regarding slimming down magnesium intake are 0.81 (95% CI: 0.69, 0.94; P-pattern = 0.001) to own full heart attack. Complete potassium intake are inversely associated with the chance of overall but maybe not ischemic otherwise hemorrhagic heart attack ( Dining table 3). To possess evaluation of women about highest with reasonable quintiles from overall potassium intake, brand new pooled multivariate RR having overall stroke are 0.89 (95% CI: 0.80, 0.99; P-trend = 0.01). Multivariate RRs for both magnesium and you may potassium was basically attenuated when most of the step 3 nutritional elements was in fact within the habits additionally (multivariate model 2). There can be no high association ranging from full or weightloss calcium consumption and full, ischemic, or hemorrhagic coronary arrest ( Desk cuatro). Multivariate RRs to have total magnesium (Supplemental Desk 1), full potassium (Supplemental Desk dos), total calcium (Supplemental Desk step 3), fat loss magnesium (Extra Dining table cuatro), fat reduction potassium (Supplemental Dining table 5), and you will weight-loss calcium supplements (Supplemental Table 6) and chance of full, ischemic, Lesbian dating and you will hemorrhagic strokes for every cohort separately are offered on supplemental issue.
Pooled RRs (95% CIs) out-of total, ischemic, and hemorrhagic shots of the quintiles of full and fat loss magnesium intake during the 86,149 women in brand new NHS I and you can 94,715 ladies in the newest NHS II step one
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.
Pooled RRs (95% CIs) of complete, ischemic, and you will hemorrhagic shots from the quintiles away from complete and you may diet magnesium consumption inside the 86,149 feamales in the newest NHS We and you may 94,715 ladies in the fresh NHS II step one
Values are the n of cases. Cox proportional hazards models were used to estimate RRs and 95% CIs. Model 1 was adjusted for age, calendar year, total calories (quintiles of kcal), BMI (in kg/m 2 ; <25, 25 to <30, or ?30), parental history of heart disease (aged ?60 y), alcohol intake (0, 0 to <5, 5 to <10, 10 to <15, or ?15 g/d), physical activity (<3, 3 to <9, 9 to<18, 18 to <27, or ?27 metabolic equivalent tasks/wk), smoking, postmenopausal hormone therapy, oral contraceptive use (never, past, or current), menopausal status (premenopausal or postmenopausal), aspirin (0 to <2 or ?2 pills/wk), multivitamin, history of hypertension, hypercholesterolemia, diabetes at baseline, and thiazide use (yes or no). NHS, Nurses' Health Study.